职  称:教授
研究方向:活性分子合成,金属有机方法学
办公电话:
办公地点:逸夫科学馆205室

个人简历

江西樟树人。2010年在兰州大学化学基地班获得学士学位之后,被保送至北京大学化学与分子工程学院杨震教授课题组攻读有机化学博士学位。2015年7月博士毕业之后,进入美国伊利诺伊大学香槟分校化学系David Sarlah课题组从事博士后研究工作。2016年底加入东北师范大学化学院有机化学专业,副教授,博士生导师。2021年晋升为教授。 主要研究方向为新颖有机方法学的开发及其在活性天然产物全合成中的应用,完成了包括cortistatin A, tuberostemospiroline,stemona-lactam R等多个复杂天然产物的全合成或形式全合成,部分工作被Organic Chemistry Portal亮点评述。在Nat. Chem., J. Am. Chem. Soc., Chem, Nat. Comm., Angew. Chem. Int. Ed., ACS Catal.等杂志上发表论文30余篇。已获得国家自然科学基金青年项目(2017)和面上项目(2019,2023),以及吉林省优秀青年基金(2023)等资助。 课题组主页:https://www.x-mol.com/groups/fu_junkai 我们热烈欢迎对金属有机化学,天然产物全合成感兴趣的研究生加入。 发表论文: 35.Zhao, C.;† Gao, R.;† Ma, W.; Li, M.; Li, Y.; Zhang, Q.; Guan, W.;* Fu, J.-K.* “A Facile Synthesis of α,β-Unsaturated Imines via Palladium-Catalyzed Dehydrogenation”, Nat. Commun. 2024, 15, 4329. (†equal contribution) 34.Dong, J.;† Liang, Y.;† Li, Y.;† Guan, W.;* Zhang, Q.; Fu, J.-K.* “A Catalytic Three-Component Aminofluorination of Unactivated Alkenes with Electron-Rich Amino Sources”, Adv. Sci. 2024, 11, 2305006. (†equal contribution) 33.Wang, T.;†,* Yu, W.;† Lan, J.;† Wang, H.; Jiang, Z.; Li, Y.; Fu, J.-K.* “Visible-Light-Driven Three-Component Reductive 1,2-Diarylation of Alkenes”, Chem Catal. 2023, 3, 100619. (†equal contribution) 32. Li, Y.;† Dong, Y.;† Wang, X.;† Li, G.; Xue, H.; Xin, W.; Zhang, Q.; Guan, W.*; Fu, J.-K.* “Regio-, Site- and Stereoselective Three-Component Aminofluorination of 1,3-Dienes via Cooperative Silver Salt and Copper Catalysis”, ACS Catal. 2023, 13, 2410-2421. (†equal contribution) 31. Zhao, C.;† Li, Y.;† Dong, Y.;† Li, M.; Xia, D.; Gao, S.; Zhang, Q.; Liu, Q.; Guan, W.*; Fu, J.-K.* “Divergent Regioselective Heck-type Reaction of Unactivated Alkenes and N-Fluoro-sulfonamides”, Nat. Commun. 2022, 13, 6297. (†equal contribution) 30. Zhao, C.; Zhu, D.-S.*; Fu, J.-K.* “Alkene difunctionalization via aminyl radicals”, Trends in Chemistry 2022, doi: org/10.1016/j.trechm.2022.08.003. (Invited Review, MOM) 29. Huo, L.-Q.; Shi, L.-L.*; Fu, J.-K.* “Iron-Copper Dual Catalysis Enabling C−C and C−X (X = N, B, P, S, Sn) Bond Formation”, Eur. J. Org. Chem. 2022, e202200454. (Invited Review) 28. Yang, L.;† Huang, Y.;† Yu, W.; Fan, L.; Wang, T.*; Fu, J.-K.*“Copper-Catalyzed Oxidative Coupling of Quinazoline-3-Oxides: Synthesis of O-Quinazolinic Carbamates”, J. Org. Chem. 2022, 87, 5136-5148. (†equal contribution) 27. Li, Y.;† Bao, J.;† Zhang, Y.; Peng, X.; Yu, W.; Wang, T.; Yang, D.; Liu, Q.; Zhang, Q.; Fu, J.-K.*“Three-Component Aminofluorination of Alkenes with Electronically Rich Amino Sources”, Chem 2022, 8, 1147-1163. (†equal contribution) 26. Wang, X.; Li, D.; Zhang, J.-L.; Gong, J.-X.; Fu, J.-K.*; Yang, Z.*“A Synthetic Route to The Core Structure of (−)-Retigeranic Acid A”, Org. Lett. 2021, 23, 5092-5097. 25. Li, Y.;† Ali, A.;† Dong, J.; Zhang, Y.; Shi, L.-L.; Liu, Q.; Fu, J.-K.*“Copper-Catalyzed Diamination of Unactivated Alkenes With Electron-Rich Amino Sources”,Org. Lett. 2021, 23, 4072-4077. (†equal contribution) 24. Liu, S.-Z.;† Yang, L.-Y.;† Tao, J.-S.; Yu, W.-J.; Wang, T.*; Fu, J.-K.*“Nickel-Catalyzed Oxidative Transamidation of Tertiary Aromatic Amines with N-Acylsaccharins”, Synlett 2021, 32, 1642-1646. (Invited Article by R. Martin, as part of the Cluster "Modern Nickel-Catalyzed Reactions") (†equal contribution) "Featured in Org. Chem. Highlights" (https://www.organic-chemistry.org/Highlights/2022/27June.shtm) 23. Gao, S.-Q.; Shi, L.-L.*; Chang, L.; Wang, B.-L.; Fu, J.-K.*“Recent Developments in Heck-Type Reaction of Unactivated Alkenes and Alkyl Electrophiles”, Synthesis 2021, 53, 861-878. (Invited Review) 22. Zhang, Z.-C.;† Zhao, D.-D.;† Zhang, Z.-C.; Tan, X.-Y.; Gong, J.-X.*; Fu, J.-K.*; Yang, Z.* “Synthesis of 4-Desmethyl-rippertenol and 7-Epi-rippertenol via Photo-induced Cyclization of Dienones”, CCS Chemistry, 2020, 2, 2074-2083. (†equal contribution) 21. Deng, Y.;† Zhao, C.;† Zhou, Y.;† Wang, H.; Li, X.; Cheng, G.-J.; Fu, J.-K.* “Directing-Group-Based Strategy Enabling Intermolecular Heck-Type Reaction of Cycloketone Oxime Esters and Unactivated Alkenes”, Org. Lett. 2020, 22, 3524-3530. (†equal contribution) 20. Li, Y.;† Liang, Y.-J.;† Dong, J.-C.; Deng, Y.; Zhao, C.-Y.; Su, Z.-M.; Guan, W.*; Bi, X.-H.*; Liu, Q.; Fu, J.-K.* “Directed Copper-Catalyzed Intermolecular Aminative Difunctionalization of Unactivated Alkenes”, J. Am. Chem. Soc. 2019, 141, 18475. (Cover, †equal contribution) 东师主页报道 http://www.nenu.edu.cn/info/1055/11203.htm “研之成理”微信公众号推送 https://mp.weixin.qq.com/s/PBHMGzQdeDEjmJmdCVWm2g “化学加”微信公众号推送 https://mp.weixin.qq.com/s/NkCyc3NAXh5JBH8xZPWQyQ 东北师大官方微信公众号推送 https://mp.weixin.qq.com/s/1XtEIADF8jWgZQuppUHSLg 19. Yu, W.-J.; Chen, L.; Tao, J.-S.; Wang, T.*; Fu, J.-K.* “Dual Nickel- and Photoredox-Catalyzed Reductive Cross-coupling of Aryl Vinyl Halides and Unactivated Tertiary Alkyl Bromides”, Chem. Commun. 2019, 55, 5918-5921. 18. Tian, L.; Gao, S.-Q.; Wang, R.; Li, Y.; Tang, C.-L.; Shi, L.-L.*; Fu, J.-K.* “Copper-catalyzed Ring-opening C(sp3)-N Coupling of Cycloketone Oxime Esters: Access to 1º, 2º and 3º Alkyl Amines”, Chem. Commun. 2019, 55, 5347-5350. 17. Tang, C.-L.;† Zhang, R.;† Zhu, B.;† Fu, J.-K.*; Deng, Y.; Tian, L.; Guan, W.*; Bi, X.-H.* “Directed Copper-Catalyzed Intermolecular Heck-Type Reaction of Unactivated Olefins and Alkyl Halides”, J. Am. Chem. Soc. 2018, 140, 16929-16935. (Cover, †equal contribution) 东师主页报道 http://www.nenu.edu.cn/2018/1122/c139a33334/page.htm CBG资讯报道 https://www.chembeango.com/zixun/32859 16. Yu, W.-J.; Yang, S.-W.; Xiong, F.; Fan, T.-X.; Feng, Y.; Huang, Y.-Y.; Fu, J.-K.*; Wang, T.* “Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters via C–N bond activation”, Org. Biomol. Chem. 2018, 16, 3099-3103. 15. Li, Y.; Zhang, R.; Bi, X.-H.*; Fu, J.-K.* “Multifunctionalization of Unactivated Cyclic Ketones via Synergistic Catalysis of Copper and Diarylamine: Access to Cyclic α‑Enaminone”, Org. Lett. 2018, 20, 1207-1211. 14. Fu, J.-K.; Zanoni, G.; Anderson, E. A.; Bi, X.-H.* “α-Substituted vinyl azides: an emerging functionalized alkene”, Chem. Soc. Rev. 2017, 46, 7208-7228. 13. Zhang, R.; Li, Y.; Ali, A.; Hao, J.-M.; Bi, X.-H.*; Fu, J.-K.* “Rh(II)-Catalyzed Tandem Cyclization of Aliphatic N-Sulfonyl-1,2,3-triazoles and Alcohols for the Synthesis of 6-Alkoxy Piperidin-3-ones”, Adv. Synth. Catal. 2017, 359, 4057-4061. 12. Gu, Y.-Q.; Yuan, H.; Fu, J.-K.*; Gong, J.-X.*; Yang, Z.* “Asymmetric Formal Synthesis of Cortistatins via a Gold-Catalyzed Semi-Pinacol Rearrangement Strategy”, Acta Chim. Sinica 2017, 75, 798-807. (Invited Article) 11. Li, Y.; Zhang, R.; Ali, A.; Zhang, J.; Bi, X.-H.*; Fu, J.-K.* “Synthesis of 6-Substituted Piperidin-3-ones via Rh(II)-Catalyzed Transannulation of N-Sulfonyl-1,2,3-triazoles with Electron-Rich Aromatic Nucleophiles”, Org. Lett. 2017, 19, 3087-3090. 10. Fang, G.-C.; Liu, J.-Q.; Fu, J.-K.*; Liu, Q.; Bi, X.-H.* “Silver-Catalyzed Cascade Reaction of β-Enaminones and Isocyanoacetates To Construct Functionalized Pyrroles”, Org. Lett. 2017, 19, 1346-1349. Before NENU: 9. Fu, J.-K.; Gu, Y.-Q.; Yuan, H.; Luo, T.-P.; Liu, S.; Lan, Y.*; Gong, J.-X.*; Yang, Z.* “Towards a general diastereoselective route to oxabicyclo[3.2.1]octanes via a gold-catalysed cascade reaction”, Nat. Commun. 2015, 6, 8617. 8. Fu, J.-K.; Shen, H.-J.; Chang, Y.-Y.; Li, C.-C.; Gong, J.-X.; Yang, Z.* “Concise Stereoselective Synthesis of Oxaspirocycles with 1-Tosyl-1,2,3-triazoles: Application to the Total Syntheses of (±)-Tuberostemospiroline and (±)-Stemona-lactam R”, Chem. Eur. J. 2014, 20, 12881-12888. (Highlighted in Org. Chem., May, 11th, 2015) 7. Fu, J.-K.; Shang, H.; Wang, Z.-F.; Chang, L.; Shao, W.-B.; Yang, Z.*; Tang, Y.-F.* “Gold-Catalyzed Rearrangement of Allylic Oxonium Ylides: Efficient Synthesis of Highly Functionalized Dihydrofuran-3-ones”, Angew. Chem. Int. Ed. 2013, 52, 4198-4202. 6. Southgate, E.;† Pospech, J.;† Fu, J.-K.; Holycross, D. R.; Sarlah, D.* “Dearomative Dihydroxylation with Arenophiles”, Nat. Chem. 2016, 8, 922-928. (†equal contribution) 5. Shen, H.-J.; Fu, J.-K.; Hao, Y.; Gong, J.-X.*; Yang, Z*. “Synthesis of 2,3-Disubstituted Indoles and Benzofurans by the Tandem Reaction of Rhodium(II)-Catalyzed Intramolecular C–H Insertion and Oxygen-Mediated Oxidation”, J. Org. Chem. 2016, 81, 10180-10192. 4. Gu, Y.-Q.; Zhang, P.-P.; Fu, J.-K.; Liu, S.; Lan, Y.*; Gong, J.-X.*; Yang, Z.* “Regio- and Stereoselective Syntheses of 7-Oxabicyclo[2.2.1]heptanes via a Gold(I)-Catalyzed Cycloisomerization of Alkynediols: Asymmetric Total Synthesis of Farnesiferol C”, Adv. Synth. Catal. 2016, 358, 1392-1397. 3. Shen, H.-J.; Fu, J.-K.; Gong, J.-X.*; Yang, Z.* “Tunable and Chemoselective Syntheses of Dihydroisobenzofurans and Indanones via Rhodium-Catalyzed Tandem Reactions of 2-Triazole-benzaldehydes and 2-Triazole-alkylaryl ketones”, Org. Lett. 2014, 16, 5588-5591. 2. Wang, Z.-F.; Zhao, K.; Fu, J.-K.; Zhang, J.-L.; Yin, W.-Y.; Tang, Y. F.* “Organocatalytic 1,4-Conjugate Addition of Ascorbic Acid to α,β-unsaturated Aldehydes: Bio-inspired Total Syntheses of Leucodrin, Leudrin and Proposed Structure of Dilaspirolactone”, Org. Biomol. Chem. 2013, 11, 2093-2097. 1. Chang, L.; Jiang, H.; Fu, J.-K.; Liu, B.; Li, C.-C.*; Yang, Z*. “Synthesizing the Tetracyclic Core of Nanolobatolide”, J. Org. Chem. 2012, 77, 3609-3614.

社会兼职

获奖情况 (数据来源:科学技术处、社会科学处)

教学信息 (数据来源:教务处)

  • 诺贝尔化学奖启示

科研信息 (数据来源:科学技术处、社会科学处)

  • 项目:
  • 1. 烷基氮自由基介导的烯烃氨化双官能团化反应的研究,国家自然科学基金项目,2023年
  • 2. 非活化烯烃参与的区域选择性可调控Heck类型反应的研究,省、市、自治区科技项目,2023年
  • 3. 基于导向基团策略的烷基亲电体与非活化烯烃的Heck类型反应,国家自然科学基金项目,2019年
  • 4. 铑催化N-磺酰基三氮唑串联重排反应构建哌啶-3-酮类化合物的研究,省、市、自治区科技项目,2018年
  • 5. 新型正离子诱导的多烯串联环化反应,其他课题,2018年
  • 6. pyripyropene家族天然产物的多样性合成研究,省、市、自治区科技项目,2018年
  • 7. 亚硝酰正离子诱导多烯串联环化反应的研究,国家自然科学基金项目,2017年
  • 论文:
  • 1. Divergent regioselective Heck-type reaction of unactivated alkenes and N-fluoro-sulfonamides,NATURE COMMUNICATIONS,2022年
  • 2. Alkene difunctionalization via aminyl radicals,TRENDS IN CHEMISTRY,2022年
  • 3. Three-component aminofluorination of alkenes with electronically rich amino sources,CHEM,2022年
  • 4. Copper-Catalyzed Oxidative Coupling of Quinazoline-3-Oxides: Synthesis of O-Quinazolinic Carbamates,JOURNAL OF ORGANIC CHEMISTRY,2022年
  • 5. A Synthetic Route to The Core Structure of (-)-Retigeranic Acid A,ORGANIC LETTERS,2021年
  • 6. Nickel-Catalyzed Oxidative Transamidation of Tertiary Aromatic Amines with N-Acylsaccharins,SYNLETT,2021年
  • 7. Copper-Catalyzed Diamination of Unactivated Alkenes With Electron-Rich Amino Sources,ORGANIC LETTERS,2021年
  • 8. Recent Developments in Heck-Type Reaction of Unactivated Alkenes and Alkyl Electrophiles,SYNTHESIS-STUTTGART,2021年
  • 9. Synthesis of 4-Desmethyl-Rippertenol and 7-Epi-Rippertenol via Photoinduced Cyclization of Dienones,CCS Chemistry,2020年
  • 10. Directing-Group-Based Strategy Enabling Intermolecular Heck-Type Reaction of Cycloketone Oxime Esters and Unactivated Alkenes,ORG LETT,2020年
  • 11. Directed Copper-Catalyzed Intermolecular Aminative Difunctionalization of Unactivated Alkenes,J AM CHEM SOC,2019年
  • 12. Dual nickel- and photoredox-catalyzed reductive cross-coupling of aryl vinyl halides and unactivated tertiary alkyl bromides,CHEM COMMUN,2019年
  • 13. Copper-catalyzed Ring-opening C(sp3)-N Coupling of Cycloketone Oxime Esters: Access to 1o, 2o and 3o Alkyl Amines,CHEM COMMUN,2019年
  • 14. Directed Copper-Catalyzed Intermolecular Heck-Type Reaction of Unactivated Olefins and Alkyl Halides,J AM CHEM SOC,2018年
  • 15. Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters via C-N bond activation,ORG BIOMOL CHEM,2018年
  • 16. Multifunctionalization of Unactivated Cyclic Ketones via Synergistic Catalysis of Copper and Diarylamine:: Access to Cyclic a-Enaminone,ORG LETT,2018年
  • 17. a-Substituted vinyl azides: an emerging functionalized alkene,CHEM SOC REV,2017年
  • 18. Rh(II)-Catalyzed Tandem Cyclization of Aliphatic N-Sulfonyl-1,2,3-triazoles and Alcohols for the Synthesis of 6-Alkoxy Piperidin-3-ones,ADV SYNTH CATAL,2017年
  • 19. Cortistatin 类型天然产物的不对称形式全合成: 金催化串联 Semi-Pinacol 重排反应策略,ACTA CHIM SINICA,2017年
  • 20. Synthesis of 6-Substituted Piperidin-3-ones via Rh(II)-Catalyzed Transannulation of N-Sulfonyl-1,2,3-triazoles with Electron-Rich Aromatic Nucleophiles,ORG LETT,2017年
  • 21. Silver-Catalyzed Cascade Reaction of b-Enaminones and Isocyanoacetates To Construct Functionalized Pyrroles,ORG LETT,2017年
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