职  称:教授
研究方向:
办公电话:YANGL330@nenu.edu.cn
办公地点:逸夫科技馆436
电子邮件:yangl330@nenu.edu.cn

个人简历

杨丽,女。东北师范大学化学学院,教授,博士生导师。2002年毕业于中国科学技术大学,获博士学位。其后在欧洲和美国研究机构从事博士后研究工作。2008年被东北师范大学优秀学术骨干引进,入选东北师范大学“东师学者”青年学术骨干培养计划。主要研究方向为发展以毛细管电泳/电色谱为基础的复杂样品和痕量物质的分离分析技术。至今已在Anal. Chem., J. Chromatgr. A, Anal. Chim. Acta, Mol. Cell. Proteomics, J. Proteome Res.等刊物上发表SCI 收录论文40余篇,主持国家基金委、教育部、吉林省科技厅等多项科研项目。 研究方向: 新分离分析技术在生物分析及复杂样品分析中的研究与应用 受教育经历: 1998/09 - 2002/06,中国科学技术大学,化学系,博士 1997/09 - 1998/06,中国科学技术大学,化学系,硕士 1993/09 - 1997/06,中国科学技术大学,应用化学系,学士 研究工作经历: 2014/02 - 至今, 东北师范大学,化学学院,教授,博士生导师 2008/02 - 2014/2, 东北师范大学,化学学院,副教授,博士生导师 2006/07 - 2007/12,美国Calibrant Biosystem,Inc. & 美国马里兰大学,博士后 2005/04 - 2006/06,美国路易斯安那州立大学,化学系,博士后 2003/07 - 2004/10,爱尔兰科克大学,化学系,博士后 教学任务: 高等分析化学 分析化学 化合物成分分析实验 Chromatography (留学生研究生课程) 科研项目: 1)国家自然科学基金面上项目,21475019、“基于毛细管电泳技术的微生物胞内目标代谢物在线分析”、2015/01-2018/12、80万元、在研、主持。 2)国家自然科学基金面上项目,21175018、“以毛细管电泳为基础的酶切多肽反应全程的高时间分辨检测技术及应用研究”、2012/01-2015/12、56万元、在研、主持。 3)吉林省科技厅重点项目,20120431、“基于液液微萃取-高效毛细管电泳技术联用的生物检材中痕量滥用药物的快速灵敏检测”、2012/01-2014/12、15万元、在研、主持。 4)东北师范大学“东师学者”青年学术骨干培养计划,2012/01-2014/12、10万元、在研、主持。 5)国家自然科学基金青年项目、20805005、“光快门漂白进样-电泳媒介微分析法连用的毛细管电泳在线酶反应研究平台”、2009/01-2011/12、20万元、已结题、主持。 6)教育部新教师基金、200802001014、“开管毛细管固定化酶反应器与双酶底物循环法联用的毛细管电泳谷氨酸测定平台”、2009/01-2011/12、3.6万元、已结题、主持。 7)教育部留学回国基金、“利用开管毛细管固定化酶反应器的毛细管电泳法测定痕量谷氨酸”、2009/01-2011/12、3.0万元、已结题、主持。 8)吉林省科技厅青年基金、20080118、“开管毛细管电色谱测定痕量谷氨酸”、2008/10-2010/10、6万元、已结题、主持。 9)国家“863”计划课题、2013AA032204、“ 面向公共安全用纳米材料及诊断技术的研发”、2013/12-2016/12、1234万元、在研、课题骨干。 10)国家科技支撑计划项目子课题、2012BAK02B04、“物证检验与溯源关键技术与装备研发”、2012/2-2014/12、525万元、在研、课题骨干。 主要研究论文 •1. Photonic crystal fiber-based immunosensor for high-performance detection of alpha fetoprotein,BIOSENS BIOELECTRON,2017年 •2. Facile synthesis of electrospinning Mn2O3-Fe2O3 loaded carbon fibers for electrocatalysis of hydrogen peroxide reduction and hydrazine oxidation,ELECTROCHIM ACTA,2016年 •3. Capillary Zone Electrophoresis as a Tool to Monitor the Stability and Hydrolytic Equilibria of Strandberg-Type Polyoxometalates in Aqueous Solution,EUR J INORG CHEM,2016年 •4. Enzyme and inhibition assay of urease by continuous monitoring of the ammonium formation based on capillary electrophoresis,ELECTROPHORESIS,2016年 •5. 基于毛细管电泳技术的毒品检验与溯源,分子科学学报,2016年 •6. Sequential on-line C-terminal sequencing of peptides based on carboxypeptidase Y digestion and optically gated capillary electrophoresis with laser-induced fluorescence detection,J CHROMATOGR A,2016年 •7. Capillary electrophoresis-integrated immobilized enzyme reactors,REV ANAL CHEM,2016年 •8. Determination of the inhibitory effect of green tea extract on glucose-6-phosphate dehydrogenase based on multilayer capillary enzyme microreactor,BIOMED CHROMATOGR,2016年 •9. Sequential capillary electrophoresis analysis using optically gated sample injection and UV/vis detection,ELECTROPHORESIS,2015年 •10. On-plate enzyme and inhibition assay of glucose-6-phosphate dehydrogenase using thin-layer chromatography,J SEP SCI,2015年 •11. Application of Thin-Layer Chromatography in Enzyme Activity and Inhibitors Studies of Glucose-6-Phosphate Dehydrogenase,JPC-J PLANAR CHROMAT,2015年 •12. Application of capillary enzyme micro-reactor in enzyme activity and inhibitors studies of glucose-6-phosphate dehydrogenase,J CHROMATOGR B,2015年 •13. Enhancing separation in short-capillary electrophoresis via pressure-driven backflow,ELECTROPHORESIS,2015年 •14. Theoretical and experimental studies on sequential two-diffusional sample injection for capillary electrophoresis,J CHROMATOGR A,2015年 •15. Inhibition study of alanine aminotransferase enzyme using sequential online capillary electrophoresis analysis,ANAL BIOCHEM,2014年 •16. Capillary electrophoresis-based immobilized enzyme reactor using particle-packing technique,J CHROMATOGR A,2014年 •17. A capillary electrophoresis-based immobilized enzyme reactor using graphene oxide as a support via layer by layer electrostatic assembly,ANALYST,2014年 •18. Efficient capillary electrophoresis separation and determination of free amino acids in beer samples,ELECTROPHORESIS,2014年 •19. Sequential micellar electrokinetic chromatography analysis of racemization reaction of alanine enantiomers,J CHROMATOGR A,2014年 •20. Ionic Liquid-Based Dispersive Liquid-Liquid Microextraction Coupled with Capillary Electrophoresis to Determine Drugs of Abuse in Urine,CHINESE J ANAL CHEM,2013年 •21. Graphene oxide and reduced graphene oxide as novel stationary phases via electrostatic assembly for open-tubular capillary electrochromatography,ELECTROPHORESIS,2013年 •22. Application of cyclodextrin-modified gold nanoparticles in enantioselective monolith capillary electrochromatography,TALANTA,2013年 •23. Application of graphene as the stationary phase for open-tubular capillary electrochromatography,J CHROMATOGR A,2013年 •24. Electrochemistry and Simultaneous Detection of Metabolites of Purine Nucleotide Based on Large Mesoporous Carbon Modified Electrode,ELECTROANAL,2012年 •25. Online Enzyme Discrimination and Determination of Substrate Enantiomers Based on Electrophoretically Mediated Microanalysis,ANAL CHEM,2012年 •26. A replaceable dual-enzyme capillary microreactor using magnetic beads and its application for simultaneous detection of acetaldehyde and pyruvate,ELECTROPHORESIS,2012年 •27. Method for the Sequential Online Analysis of Enzyme Reactions Based on Capillary Electrophoresis,ANAL CHEM,2012年 •28. 爆炸残留物的毛细管电泳检测, 陈春杨,卡不列江.卡旦,陈翠杰,杨丽*,张军富,谢文林, 分析化学,39 (2011) 1293-1294 •29. Enantioselective open-tubular capillary electrochromatography using cyclodextrin-modified gold nanoparticles as stationary phase, Min Li, Xi Liu, Fengyi Jiang, Liping Guo, Li Yang*, J Chromatogr A, 1218 (2011) 3725-3729

社会兼职

获奖情况 (数据来源:科学技术处、社会科学处)

教学信息 (数据来源:教务处)

  • 高等分析化学
  • 分析化学
  • 化合物成分分析实验

科研信息 (数据来源:科学技术处、社会科学处)

  • 项目:
  • 1. 生物质转化微通道催化反应器的设计与实时在线检,2018年
  • 2. 口服固体药物制剂体外溶出度的高时间分辨在线过程分析,2017年
  • 3. 基于毛细管电泳技术的微生物胞内目标代谢物在线分析,2014年
  • 4. 基于液液微萃取-高效毛细管电泳技术联用的生物检材中痕量滥用药物的快速灵敏检测,吉林省科技厅,2012年
  • 专著:
  • 1. 仪器分析实验,科学出版社,01-5年
  • 2. 分析化学(科学出版社),科学出版社,01-1年
  • 论文:
  • 1. Screening Platform Based on Robolid Microplate for Immobilized Enzyme-Based Assays,ACS Omega,2017年
  • 2. Core-shell silica microsphere-based trypsin nanoreactor for low molecular-weight proteome analysis,ANAL CHIM ACTA,2017年
  • 3. Photonic crystal fiber-based immunosensor for high-performance detection of alpha fetoprotein,BIOSENS BIOELECTRON,2017年
  • 4. Facile synthesis of electrospinning Mn2O3-Fe2O3 loaded carbon fibers for electrocatalysis of hydrogen peroxide reduction and hydrazine oxidation,ELECTROCHIM ACTA,2016年
  • 5. Capillary Zone Electrophoresis as a Tool to Monitor the Stability and Hydrolytic Equilibria of Strandberg-Type Polyoxometalates in Aqueous Solution,EUR J INORG CHEM,2016年
  • 6. 基于毛细管电泳技术的毒品检验与溯源,分子科学学报,2016年
  • 7. Enzyme and inhibition assay of urease by continuous monitoring of the ammonium formation based on capillary electrophoresis,ELECTROPHORESIS,2016年
  • 8. Sequential on-line C-terminal sequencing of peptides based on carboxypeptidase Y digestion and optically gated capillary electrophoresis with laser-induced fluorescence detection,J CHROMATOGR A,2016年
  • 9. Capillary electrophoresis-integrated immobilized enzyme reactors,REV ANAL CHEM,2016年
  • 10. Determination of the inhibitory effect of green tea extract on glucose-6-phosphate dehydrogenase based on multilayer capillary enzyme microreactor,BIOMED CHROMATOGR,2016年
  • 11. Sequential capillary electrophoresis analysis using optically gated sample injection and UV/vis detection,ELECTROPHORESIS,2015年
  • 12. On-plate enzyme and inhibition assay of glucose-6-phosphate dehydrogenase using thin-layer chromatography,J SEP SCI,2015年
  • 13. Application of Thin-Layer Chromatography in Enzyme Activity and Inhibitors Studies of Glucose-6-Phosphate Dehydrogenase,JPC-J PLANAR CHROMAT,2015年
  • 14. Application of capillary enzyme micro-reactor in enzyme activity and inhibitors studies of glucose-6-phosphate dehydrogenase,J CHROMATOGR B,2015年
  • 15. Enhancing separation in short-capillary electrophoresis via pressure-driven backflow,ELECTROPHORESIS,2015年
  • 16. Theoretical and experimental studies on sequential two-diffusional sample injection for capillary electrophoresis,J CHROMATOGR A,2015年
  • 17. Inhibition study of alanine aminotransferase enzyme using sequential online capillary electrophoresis analysis,ANAL BIOCHEM,2014年
  • 18. Capillary electrophoresis-based immobilized enzyme reactor using particle-packing technique,J CHROMATOGR A,2014年
  • 19. Efficient capillary electrophoresis separation and determination of free amino acids in beer samples,ELECTROPHORESIS,2014年
  • 20. A capillary electrophoresis-based immobilized enzyme reactor using graphene oxide as a support via layer by layer electrostatic assembly,ANALYST,2014年
  • 21. Sequential micellar electrokinetic chromatography analysis of racemization reaction of alanine enantiomers,J CHROMATOGR A,2014年
  • 22. Ionic Liquid-Based Dispersive Liquid-Liquid Microextraction Coupled with Capillary Electrophoresis to Determine Drugs of Abuse in Urine,CHINESE J ANAL CHEM,2013年
  • 23. Graphene oxide and reduced graphene oxide as novel stationary phases via electrostatic assembly for open-tubular capillary electrochromatography,ELECTROPHORESIS,2013年
  • 24. Application of cyclodextrin-modified gold nanoparticles in enantioselective monolith capillary electrochromatography,TALANTA,2013年
  • 25. Application of graphene as the stationary phase for open-tubular capillary electrochromatography,J CHROMATOGR A,2013年
  • 26. Online Enzyme Discrimination and Determination of Substrate Enantiomers Based on Electrophoretically Mediated Microanalysis,ANAL CHEM,2012年
  • 27. Electrochemistry and Simultaneous Detection of Metabolites of Purine Nucleotide Based on Large Mesoporous Carbon Modified Electrode,ELECTROANAL,2012年
  • 28. A replaceable dual-enzyme capillary microreactor using magnetic beads and its application for simultaneous detection of acetaldehyde and pyruvate,ELECTROPHORESIS,2012年
  • 29. Method for the Sequential Online Analysis of Enzyme Reactions Based on Capillary Electrophoresis,ANAL CHEM,2012年
信息维护