职  称:教授
研究方向:糖复合物的结构与功能
办公电话:85098212
办公地点:长春市人民大街5268号,东北师范大学生命科学学院综合实验楼

个人简历

周义发教授,博士生导师,长白山学者特聘教授,吉林省高级专家。1988年硕士毕业于东北师范大学生命科学学院,留校一直从事糖类化合物结构与功能的研究,1993年破格提为副教授。1994年前往德国歌廷根大学攻读博士,1998年获得博士学位。1999年前往加拿大萨斯喀彻温大学做博士后,2000年9月任加拿大科学院Steacie分子科学研究所研究员。2001年10月加入美国和新加坡政府联合组建的药物研发公司CHIRON-SBIO,任高级研究员。2004年3月回到东北师大生命科学院工作,从事糖复合物的结构与功能的研究。 学历    1979, 09—1983, 07: 东北师范大学化学系, 本科生   1985, 09—1988, 07: 东北师范大学生物系, 生物化学硕士生   1994, 09—1998, 11: 德国歌廷根大学,生物有机化学博士生    工作简历   1988,09—1993,08: 东北师范大学生命科学学院,讲师   1993,09—1994,07: 东北师范大学生命科学学院,副教授   1994,08—1999,10: 德国歌廷根,歌廷根大学,研究助理   1999,10—2000,09: 加拿大,萨斯喀彻温大学,博士后    2000,10—2001,09: 加拿大科学院,分子科学研究所,研究员   2001,10—2004,03: 美国-新加坡,Chiron-S*bio药物研究公司,高级研究员   2004,04—2013,03: 东北师范大学生命科学学院教授,博士生导师,副院长 2013,04—2021,05: 东北师范大学生命科学学院教授,博士生导师,院长 2021,06— : 东北师范大学生命科学学院教授,博士生导师,糖复合物教育部工程中心主任

社会兼职

获奖情况

  • 获奖情况:
    1993-10-01 吉林省教委科技进步二等奖
    1986-01-01 国家教委科技进步二等奖
    2014-11-04 吉林省科学技术奖自然科学奖一等奖

教学信息

  • 本科生:生物化学
    研究生:糖复合物分析技术

科研信息 (数据来源:科学技术处、社会科学处)

  • 项目:
  • 1. 糖复合物教育部工程研究中心建设,省、市、自治区科技项目,2023年
  • 2. 人参酶解技术生产大健康产品的应用与推广,省、市、自治区科技项目,2023年
  • 3. 人参及其酶解产物在护肤美容和保健康养领域的应用,企事业单位委托科技项目,2022年
  • 4. 人参茎叶皂苷调节肠道菌群保健食品的开发,省、市、自治区科技项目,2022年
  • 5. 小冰麦鉴定新技术开发,企事业单位委托科技项目,2021年
  • 6. 长白山药用植物多糖系统研究,省、市、自治区科技项目,2020年
  • 7. 中药功能多糖组分库的构建及其关键技术研究,国务院其他部门,2019年
  • 8. 中药多糖组分库构建及其关键技术研究,省、市、自治区科技项目,2019年
  • 9. 猪脑神经节苷脂GM1的制备及产业化,省、市、自治区科技项目,2017年
  • 10. 果胶分子中结构域的排列方式及精细结构分析,国家自然科学基金项目,2017年
  • 11. 生物转化制备神经节苷脂GM-1,企事业单位委托科技项目,2017年
  • 12. 吉林省长白山学者科研业务经费,省、市、自治区科技项目,2015年
  • 13. 吉林省特色动植物多糖的制备及其药物筛选技术,省、市、自治区科技项目,2015年
  • 14. 生物转化制备高活性神经系统药物GM1,省、市、自治区科技项目,2015年
  • 15. 利用低酯化向日葵果胶制备空心胶囊的技术开发,省、市、自治区科技项目,2014年
  • 16. 利用真菌作为降解工具研究果胶的结构与免疫活性的关系,国家自然科学基金项目,2014年
  • 17. 向日葵盘果胶的制备及作为酸奶添加剂的研究,省、市、自治区科技项目,2014年
  • 18. 向日葵盘果胶产品的开发与应用,省、市、自治区科技项目,2013年
  • 19. 人参果胶调节免疫活性的构效关系及其机制研究,主管部门科技项目,2013年
  • 20. 糖类药物的高效制备技术及其应用,国家科技部,2012年
  • 21. 人参果胶降血糖功能食品研制,省、市、自治区科技项目,2012年
  • 22. 利用玉米芯生物发酵生产低聚木糖技术研究,省、市、自治区科技项目,2011年
  • 23. 以单克隆抗体作为探针研究果胶结构与免疫活性的关系,国家自然科学基金项目,2011年
  • 24. 生物转化制备原料药单唾液酸四己糖神经节苷脂钠(GM1)的技术,企事业单位委托科技项目,2011年
  • 25. 人参果胶降血糖饮料的研制,省、市、自治区科技项目,2010年
  • 26. 人参果胶中酸性多糖级分的精细结构及其抗肿瘤协同作用,国家自然科学基金项目,2009年
  • 27. 高原特色生物资源高值开发关键技术示范,企事业单位委托科技项目,2009年
  • 28. 东北师范大学生物学基地——科研训练,国家自然科学基金委员会,2009年
  • 29. 两性离子多糖"氨基酸化人参果胶"诱导T细胞免疫及其抗脓肿作用,国家自然科学基金委员会,2009年
  • 30. 人参多糖作为抗肿瘤药物佐剂的研究与应用,长春净月经济开发区,2009年
  • 31. 人参多糖作为抗肿瘤药物佐剂的研究与应用(省科技厅),省、市、自治区科技项目,2009年
  • 32. 人参多糖抗肿瘤活性机理的研究,国家自然科学基金委员会,2009年
  • 33. 人参系列产品的研究与开发,吉林宏久生物科技股份有限公司,2009年
  • 34. 仿生学合成Alangium lamarckii糖苷,教育部留学回国人员科研启动基金,2009年
  • 35. 唾液酸衍生物的制备技术,企事业单位委托科技项目,2009年
  • 36. 茄科植物糖苷生物碱的结构与防御功能的关系,主管部门科技项目,2009年
  • 37. 药物中间体研制,辽源百康药业有限责任公司,2009年
  • 38. 灵孢多糖的理化性质和结构研究,企事业单位委托科技项目,2006年
  • 39. 马铃薯秧、蕃茄秧和茄秧中糖苷生物碱的研究与应用,省、市、自治区科技项目,2006年
  • 专著:
  • 1. 生物学实验基本技术与方法数字课程(分册VI),高等教育出版社;高等教育电子音像出版社,04-1年
  • 2. 生物化学简明教程(第5版),高等教育出版社,01-8年
  • 3. 现代生命科学进展,东北师范大学出版社,01-7年
  • 4. Enantioselektive Synthese der Indolalkaloide vom Vallesiachotamin- und Corynanthe-Typ durch Domino-Reaktion,Cuvillier Verlag Gottingen,01-4年
  • 5. PSP国际研究综述,复旦大学出版社,01-1年
  • 论文:
  • 1. Mannogalactoglucan from mushrooms protects pancreatic islets via restoring UPR and promotes insulin secretion in T1DM mice,FOOD SCIENCE AND HUMAN WELLNESS,2024年
  • 2. A trapped covalent intermediate as a key catalytic element in the hydrolysis of a GH3 β-glucosidase: An X-ray crystallographic and biochemical study,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2024年
  • 3. Preparation of β-galacto-oligosaccharides using a novel endo-1,4-β-galactanase from Penicillium oxalicum,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2024年
  • 4. An efficient protocol for preparing linear β-manno-oligosaccharides,CARBOHYDRATE RESEARCH,2023年
  • 5. Preparation and structural analysis of fucomannogalactan and beta-1,6-glucan from Grifola frondosa mycelium,FRONTIERS IN CHEMISTRY,2023年
  • 6. Purification and identification of oligosaccharides from Cimicifuga heracleifolia Kom. rhizomes,FOOD CHEMISTRY-X,2023年
  • 7. Structural characterization and antioxidant activity of pectic polysaccharides from Veronica peregrina L.,FRONTIERS IN NUTRITION,2023年
  • 8. 嗜糖黄杆菌β-葡萄糖苷酶的功能及在稀有人参皂苷制备中的应用,微生物学通报,2023年
  • 9. Structural characterization of water-soluble polysaccharides isolated from leaves of Hedera nepalensis,CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE,2023年
  • 10. The interrelation of galectins and autophagy,INTERNATIONAL IMMUNOPHARMACOLOGY,2023年
  • 11. The model polysaccharide potato galactan is actually a mixture of different polysaccharides,CARBOHYDRATE POLYMERS,2023年
  • 12. Ginsenoside F1 administration promotes UCP1-dependent fat browning and ameliorates obesity-associated insulin resistance,FOOD SCIENCE AND HUMAN WELLNESS,2023年
  • 13. A ginseng-derived rhamnogalacturonan I (RG-I) pectin promotes longevity via TOR signalling in Caenorhabditis elegans,CARBOHYDRATE POLYMERS,2023年
  • 14. 浸麻类芽孢杆菌葡甘露聚糖降解酶的异源表达及功能研究,微生物学报,2023年
  • 15. Heterogalactan WPEP-N-b from Pleurotus eryngii enhances immunity in immunocompromised mice,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2023年
  • 16. Structural characterization and anti-oxidation activity evaluation of pectin from Lonicera japonica Thunb.,FRONTIERS IN NUTRITION,2022年
  • 17. Galactofuranose side chains in galactomannans from Penicillium spp. modulate galectin-8-mediated bioactivity,CARBOHYDRATE POLYMERS,2022年
  • 18. Cloning, Expression, and Characterization of Endo-β-1,6-galactanase PoGal30 from Penicillium oxalicum,APPL BIOCHEM BIOTECH,2022年
  • 19. Determining Methyl-Esterification Patterns in Plant-Derived Homogalacturonan Pectins,FRONTIERS IN NUTRITION,2022年
  • 20. Ginsenoside compound K protects against obesity through pharmacological targeting of glucocorticoid receptor to activate lipophagy and lipid metabolism,PHARMACEUTICS,2022年
  • 21. Structure and antioxidant activity of six mushroom-derived heterogalactans,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2022年
  • 22. beta-1,6-Glucan From Pleurotus eryngii Modulates the Immunity and Gut Microbiota,FRONTIERS IN IMMUNOLOGY,2022年
  • 23. Comparative study of water-soluble polysaccharides isolated from leaves and roots of Isatis indigotica Fort.,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2022年
  • 24. Dual crosslinking of folic acid-modified pectin nanoparticles for enhanced oral insulin delivery,BIOMATERIALS ADVANCES,2022年
  • 25. Biochemical Characterization of Two Rhamnogalacturonan Lyases From Bacteroides ovatus ATCC 8483 With Preference for RG-I Substrates,FRONTIERS IN MICROBIOLOGY,2022年
  • 26. Simultaneous Determination of 25 Ginsenosides by UPLC-HRMS via Quantitative Analysis of Multicomponents by Single Marker,INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY,2021年
  • 27. Bee Pollen Polysaccharide From Rosa rugosa Thunb. (Rosaceae) Promotes Pancreatic β-Cell Proliferation and Insulin Secretion,FRONTIERS IN PHARMACOLOGY,2021年
  • 28. Pectic polysaccharides from Radix Sophorae Tonkinensis exhibit significant antioxidant effects,CARBOHYD POLYM,2021年
  • 29. Comparison of Analytical Methods for Determining Methylesterification and Acetylation of Pectin,APPLIED SCIENCES-BASEL,2021年
  • 30. Galectin-3 N-terminal tail prolines modulate cell activity and glycan-mediated oligomerization/ phase separation,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2021年
  • 31. Structural analysis and macrophage activation of a novel β-glucan isolated from Cantharellus cibarius,INT J MOL MED,2021年
  • 32. Comparative study on the structures of intra- and extra-cellular polysaccharides from Penicillium oxalicum and their inhibitory effects on galectins,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021年
  • 33. Citrus-derived DHCP inhibits mitochondrial complex II to enhance TRAIL sensitivity via ROS-induced DR5 upregulation,JOURNAL OF BIOLOGICAL CHEMISTRY,2021年
  • 34. Topsy-turvy binding of negatively charged homogalacturonan oligosaccharides to galectin-3,GLYCOBIOLOGY,2021年
  • 35. Protective effects of polysaccharides from Panax ginseng on acute gastric ulcers induced by ethanol in rats,FOOD & FUNCTION,2021年
  • 36. Protective effects of ginsenoside Rg2 against memory impairment and neuronal death induced by Aβ25-35 in rats,J ETHNOPHARMACOL,2021年
  • 37. The Film-Forming Characterization and Structural Analysis of Pectin from Sunflower Heads,INTERNATIONAL JOURNAL OF POLYMER SCIENCE,2021年
  • 38. Structure-function studies of galectin-14, an important effector molecule in embryology,FEBS J,2021年
  • 39. An antimicrobial peptide-immobilized nanofiber mat with superior performances than the commercial silver-containing dressing,MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2021年
  • 40. Structural characterization and immunomodulatory activity of a heterogalactan from Panax ginseng flowers,FOOD RES INT,2021年
  • 41. Glycoside hydrolase family 2 exo-β-1,6-galactosidase LpGal2 from Lactobacillus plantarum: Cloning, expression, and enzymatic characterization,PROCESS BIOCHEMISTRY,2021年
  • 42. AgNPs-incorporated nanofiber mats: Relationship between AgNPs size/content, silver release, cytotoxicity, and antibacterial activity,MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2021年
  • 43. Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity,BBA-GEN SUBJECTS,2021年
  • 44. Beta-1,6 glucan converts tumor-associated macrophages into an M1-like phenotype,CARBOHYD POLYM,2020年
  • 45. Structural analyses of the HG-type pectin from notopterygium incisum and its effects on galectins,INT J BIOL MACROMOL,2020年
  • 46. An efficient protocol for the preparation of linear arabino-oligosaccharides,CARBOHYD RES,2020年
  • 47. Antiarrhythmic effects of ginsenoside Rg2 on calcium chloride-induced arrhythmias without oral toxicity,JOURNAL OF GINSENG RESEARCH,2020年
  • 48. Degradative GH5 b-1,3-1,4-glucanase PpBglu5A for glucan in Paenibacillus polymyxa KF-1,PROCESS BIOCHEMISTRY,2020年
  • 49. Cellulose nanofibers electrospun from aqueous conditions,CELLULOSE,2020年
  • 50. Structural Characterization of Pectic Polysaccharides From Bupleurum chinense DC,NAT PROD COMMUN,2020年
  • 51. Gelatin-crosslinked pectin nanofiber mats allowing cell infiltration,MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2020年
  • 52. Structural analysis of water-soluble polysaccharides isolated from Panax notoginseng,INT J BIOL MACROMOL,2020年
  • 53. Crosslinked starch nanofibers with high mechanical strength and excellent water resistance for biomedical applications,BIOMED MATER,2020年
  • 54. Galectin-13/placental Protein 13: Redox-Active Disulfides as Switches for Regulating Structure, Function and Cellular Distribution,GLYCOBIOLOGY,2020年
  • 55. Box-Behnken design based statistical modeling for the extraction and physicochemical properties of pectin from sunflower heads and the comparison with commercial low-methoxyl pectin,SCIENTIFIC REPORTS,2020年
  • 56. Hypoglycemic effects of polysaccharides from Gomphidiaceae rutilus fruiting bodies and their mechanisms,FOOD & FUNCTION,2020年
  • 57. 生物化学综合实验课程改革探索,实验室研究与探索,2019年
  • 58. Preparation of Ganglioside GM1 by Supercritical CO2 Extraction and Immobilized Sialidase,MOLECULES,2019年
  • 59. Galactan isolated from Cantharellus cibarius modulates antitumor immune response by converting tumor-associated macrophages toward M1-like phenotype,CARBOHYD POLYM,2019年
  • 60. Polylactide nanofibers delivering doxycycline for chronic wound treatment,MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019年
  • 61. A crosslinking strategy to make neutral polysaccharide nanofibers robust and biocompatible: With konjac glucomannan as an example,CARBOHYD POLYM,2019年
  • 62. Fluorine-modified sialyl-Tn-CRM197 vaccine elicits a robust immune response,GLYCOCONJUGATE J,2019年
  • 63. NMR-based insight into galectin-3 binding to endothelial cell adhesion molecule CD146: Evidence for noncanonical interactions with the lectin's CRD b-sandwich F-face,GLYCOBIOLOGY,2019年
  • 64. A Novel PL9 Pectate Lyase from Paenibacillus polymyxa KF-1: Cloning, Expression, and Its Application in Pectin Degradation,INT J MOL SCI,2019年
  • 65. Cell-free enzymatic synthesis of GDP-l-fucose from mannose,AMB EXPRESS,2019年
  • 66. Selective effects of ginseng pectins on galectin-3-mediated T cell activation and apoptosis,CARBOHYD POLYM,2019年
  • 67. Heterologous Expression of a Thermostable a-Glucosidase from Geobacillus sp.Strain HTA-462 by Escherichia coli and Its Potential Application for Isomaltose-Oligosaccharide Synthesis,MOLECULES,2019年
  • 68. A novel linear 3-O-methylated galactan isolated from Cantharellus cibarius activates macrophages,CARBOHYD POLYM,2019年
  • 69. Analysis of pectin from Panax ginseng flower buds and their binding activities to galectin-3,INT J BIOL MACROMOL,2019年
  • 70. Structural characterization of rhamnogalacturonan domains from Panax ginseng C.A. Meyer,CARBOHYD POLYM,2019年
  • 71. Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10,GLYCOBIOLOGY,2019年
  • 72. Alkali-soluble polysaccharides from mushroom fruiting bodies improve insulin resistance,INT J BIOL MACROMOL,2019年
  • 73. Analyses of active antioxidant polysaccharides from four edible mushrooms,INT J BIOL MACROMOL,2019年
  • 74. Ginsenoside Re impacts on biotransformation products of ginsenoside Rb1 by Cellulosimicrobium cellulans sp.21 and its mechanisms,PROCESS BIOCHEM,2019年
  • 75. A 3-O-methylated heterogalactan from Pleurotus eryngii activates macrophages,CARBOHYD POLYM,2019年
  • 76. Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose,BIOSCIENCE REP,2018年
  • 77. Crosslinked pectin nanofibers with well-dispersed Ag nanoparticles: Preparation and characterization,CARBOHYD POLYM,2018年
  • 78. Screening of a Novel Polysaccharide Lyase Family 10 Pectate Lyase from Paenibacillus polymyxa KF-1: Cloning, Expression and Characterization,MOLECULES,2018年
  • 79. Components of heat-treated Helianthus annuus L. pectin inhibit tumor growth and promote immunity in a mouse CT26 tumor model,JOURNAL OF FUNCTIONAL FOODS,2018年
  • 80. Quantitative analysis of dextran in rat plasma using Q-Orbitrap mass spectrometry based on all ion fragmentation strategy,J CHROMATOGR B,2018年
  • 81. Preparation of individual galactan oligomers, their prebiotic effects, and use in estimating galactan chain length in pectin-derived polysaccharides,CARBOHYD POLYM,2018年
  • 82. CD146 interacts with galectin-3 to mediate endothelial cell migration,FEBS LETT,2018年
  • 83. Cloning and expression of a novel a‑1,3‑arabinofuranosidase from Penicillium oxalicum sp.68,AMB EXPRESS,2018年
  • 84. Structural characterization of alkali-soluble polysaccharides from Panax ginseng C. A. Meyer,ROYAL SOCIETY OPEN SCIENCE,2018年
  • 85. Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding,GLYCOBIOLOGY,2018年
  • 86. Free Fatty Acids Induce Pyroptosis in Pancreatic beta-Cells,PROG BIOCHEM BIOPHYS,2018年
  • 87. Cross-Linked Pectin Nanofibers with Enhanced Cell Adhesion,BIOMACROMOLECULES,2018年
  • 88. Galectin-13, a different prototype galectin, does not bind β-galacto-sides and forms dimers via intermolecular disulfide bridges between Cys-136 and Cys-138,SCIENTIFIC REPORTS,2018年
  • 89. Polysaccharide structure and immunological relationships of RG-I pectin from the bee pollen of Nelumbo nucifera,INT J BIOL MACROMOL,2018年
  • 90. Structure elucidation and immunomodulatory activity of a β-glucan derived from the fruiting bodies of Amillariella mellea,FOOD CHEM,2018年
  • 91. Preparing rhamnogalacturonan II domains from seven plant pectins using Penicillium oxalicum degradation and their structural comparison,CARBOHYD POLYM,2018年
  • 92. The roles and mechanisms of homogalacturonan and rhamnogalacturonan I pectins on the inhibition of cell migration,INT J BIOL MACROMOL,2018年
  • 93. Structural characterization and macrophage activation of a hetero-galactan isolated from Flammulina velutipes,CARBOHYD POLYM,2018年
  • 94. Ginsenosides and ginsenosidases in the pathobiology of ginseng-Cylindrocarpon destructans (Zinss) Scholten,PLANT PHYSIOL BIOCH,2018年
  • 95. Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function,BIOCHEM J,2017年
  • 96. Pectinate nanofiber mat with high absorbency and antibacterial activity: A potential superior wound dressing to alginate and chitosan nanofiber mats,CARBOHYD POLYM,2017年
  • 97. Ginsenoside Rg2 protects PC12 cells against b-amyloid25-35-induced apoptosis via the phosphoinositide 3-kinase/Akt pathway,CHEM-BIOL INTERACT,2017年
  • 98. 糖苷水解酶——生物转化制备活性糖苷与苷元的有效工具,微生物学报,2017年
  • 99. Structural Characterization of a Rhamnogalacturonan I Domain from Ginseng and Its Inhibitory Effect on Galectin-3,MOLECULES,2017年
  • 100. The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells,ONCOTARGET,2017年
  • 101. A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model,ONCOTARGET,2017年
  • 102. Pectic Bee Pollen Polysaccharide from Rosa rugosa Alleviates Diet-Induced Hepatic Steatosis and Insulin Resistance via Induction of AMPK/mTOR-Mediated Autophagy,MOLECULES,2017年
  • 103. High yield preparation of ganglioside GM1 using recombinant sialidase from Cellulosimicrobium cellulans,PROCESS BIOCHEM,2017年
  • 104. Cordycepin induces apoptosis in SGC-7901 cells through mitochondrial extrinsic phosphorylation of PI3K/Akt by generating ROS,INT J ONCOL,2017年
  • 105. Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology,FOOD & FUNCTION,2017年
  • 106. Effects of pectin structure and crosslinking method on the properties of crosslinked pectin nanofibers,CARBOHYD POLYM,2017年
  • 107. Identification of natural products with neuronal and metabolic benefits through autophagy induction,AUTOPHAGY,2017年
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  • 专利:
  • 一种竹节参多糖及其制备方法和应用 2023-03-17
  • 人参皂苷CK在作为降脂减肥药物中的应用 2022-02-18
  • 一种重组β-葡萄糖苷酶CB-3B及其在生产人参皂苷Rg3中的应用 2021-03-30
  • 蜜环菌提取物在治疗动物糖尿病中的应用 2020-05-12
  • 一种交联多糖纤维及其制备方法 2019-04-16
  • 一种人参多糖的提取方法及其在制备降血糖药物和食品中的应用 2018-04-13
  • 一种重组糖苷水解酶用于生物转化制备人参二醇型皂苷的工艺 2017-11-10
  • 一种生物转化制备单唾液酸四己糖神经节苷脂的方法 2017-06-30
  • 一种交联果胶纤维及其制备方法 2017-04-19
  • 一种果胶纤维及其制备方法 2017-02-01
  • 一种高HG含量向日葵果胶的分离制备方法 2016-10-26
  • 一种具有唾液酸水解酶活性的蛋白质及其应用 2016-09-28
  • 一种制备单唾液酸四己糖神经节苷脂的方法 2016-06-29
  • 一种罗布麻酸性多糖在治疗糖尿病药物中的应用 2016-06-08
  • 一种具有唾液酸水解酶活性的蛋白质的制备方法 2016-02-17
  • 人参酸性多糖在制备降血糖药物中的应用 2011-11-02
  • 一种抗疲劳人参酸性多糖的提取方法 2011-08-24
  • 以人参多糖为载体的抗肿瘤药物阿霉素复合物及制备方法 2010-11-10
  • 糖苷生物碱作为防治植物病害的农药及其应用 2010-05-19
  • 小鼠眼球吸取器 2010-05-12

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